| A11C C Vitamin D og analoger - C09D X03 Olmesartanmedoksomil, amlodipin og hydroklortiazid |
| ATC1 | A11C C Vitamin D og analoger (Vitamin D and analogues) |
| ATC2 | C09D X03 Olmesartanmedoksomil, amlodipin og hydroklortiazid (Olmesartan medoxomil, amlodipine and hydrochlorothiazide) |
| Nivå | Akademisk interesse. (les mer...) |
| Konsekvens | Økt risiko for hyperkalsemi og alkalose. Risikoen øker ytterligere hvis også kalsium blir inntatt. |
| Mekanisme | Tiazider hemmer utskillelsen av kalsium via nyrene, vitamin D øker opptaket av kalsium fra tarmen. |
| Grunnlag | Kasusrapporter |
| Referanser |
| 1. | Parfitt AM. Thiazide-induced hypercalcemia in vitamin D-treated hypoparathyroidism. Ann Intern Med 1972; 77: 557–63. Les mer... |
| 2. | Parfitt AM. The interactions of thiazide diuretics with parathyroid hormone and vitamin D. Studies in patients with hypoparathyroidism. J Clin Invest 1972; 51: 1879–88. Les mer... |
| 3. | Santos F, Smith MJV, Chan JCM. Hypercalciuria associated with long-term administration of calcitriol (1,25-dihydroxyvitamin D3). Action of hydrochlorothiazide. Am J Dis Child 1986; 140: 139–42. Les mer... |
| 4. | Alon U, Costanzo LS, Chan JCM. Additive hypocalciuric effects of amiloride and hydrochlorothiazide in patients treated with calcitriol. Miner Electrolyte Metab 1984; 10: 379–86. Les mer... |
| 5. | SPC Defevix Les mer... |