| N02B G10 Cannabinoider - V03A B16 Etanol |
ATC1 | N02B G10 Cannabinoider (Nabiximols) |
ATC2 | V03A B16 Etanol (Ethanol) |
Nivå | Bør ikke kombineres. (les mer...) |
Konsekvens | Risiko for kraftig sedasjon/alvorlig CNS-depresjon allerede ved lave konsentrasjoner av etanol. |
Mekanisme | Additive CNS-depressive effekter. |
Grunnlag | Indirekte data |
Referanser |
1. | SPC Sativex Les mer... |
2. | Stott C et al. A Phase I, open-label, randomized, crossover study in three parallel groups to evaluate the effect of Rifampicin, Ketoconazole, and Omeprazole on the pharmacokinetics of THC/CBD oromucosal spray in healthy volunteers. Spingerplus 2013; 2: 236. Les mer... |
3. | Stout SM. Exogenous cannabinoids as substrates, inhibitors, and inducers of human drug metabolizing enzymes: a systematic review. Drug metabolism Rev 2014; 46: 86-95. Les mer... |